Job Information
University of Colorado Assistant Professor-Research in Aurora, Colorado
Assistant Professor-Research - 27210 Research Faculty
Description
University of Colorado | CU Anschutz Medical Campus
Department of Neurology
Assistant Professor – Research
Position #00801083 – Requisition #27210
This posting is open to current University of Colorado employees only
- Applications are accepted electronically ONLY at www.cu.edu/cu-careers (https://apptrkr.com/get_redirect.php?id=4570222&targetURL=http://www.cu.edu/cu-careers)
The University of Colorado Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment. We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.
The University of Colorado Anschutz Medical Campus is a world-class medical destination at the forefront of transformative science, medicine, education and patient care. The campus encompasses the University of Colorado health professional schools, more than 60 centers and institutes, and two nationally ranked independent hospitals - UCHealth University of Colorado Hospital (https://apptrkr.com/get_redirect.php?id=4570222&targetURL=https://www.uchealth.org/locations/uchealth-university-of-colorado-hospital-uch/) and Children's Hospital Colorado (https://apptrkr.com/get_redirect.php?id=4570222&targetURL=https://www.childrenscolorado.org/locations/anschutz-medical-campus-aurora/) - that treat more than two million adult and pediatric patients each year. Innovative, interconnected and highly collaborative, the University of Colorado Anschutz Medical Campus delivers life-changing treatments, patient care and professional training and conducts world-renowned research fueled by over $650 million in research grants. For more information, visit www.cuanschutz.edu (https://apptrkr.com/get_redirect.php?id=4570222&targetURL=https://www.cuanschutz.edu/) .
Nature of Work
The Department of Neurology has an opening for a motivated full-time Assistant Professor - Research to lead projects investigating enterovirus biology, acute flaccid myelitis (AFM), and novel antiviral treatments in various mouse models of AFM. This position will collaborate with study colleagues at all levels of the organization. We are seeking an individual who is collaborative, communicative, caring, and highly motivated, who can think both critically and creatively, is detail oriented and organized, has a good eye for detail, is focused on quality, and is highly motivated in all areas of study coordination.
The Assistant Professor will work independently and in collaboration with Dr. Maria Nagel on research projects. Candidates will design, performance and analysis of experiments; prepare manuscripts and grants, and direct activities of professional research assistants/postdoctoral fellows working on these projects.
Examples of Work Performed
Conceptualize/lead projects to investigate novel drug therapies aimed at slowing, stopping, or reversing paralysis in various mouse models of EV-D68 induced acute flaccid myelitis.
Conceptualize/lead projects to investigate spread/entry of EV-D68 into the spinal cord in vivo (mouse model) and in vitro.
Design experiments examining the role of microglia and astrocytes in EV-D68 infection of the spinal cord and their role in the development of paralysis. Requires proficiency in IHC.
Assist and manage various components of program project life cycle that include:
Assist with Project 1 of the PI's current RO1, that investigates nucleotide differences between paralytic (US/IL/14-18952) and non-paralytic (US/CA/14-4231) EV-D68 isolates by cloning hybrid viral isolates and testing variants in a mouse model of AFM.
Assist with investigation of the role of microglia in neurologic disease caused by West Nile Virus.
Working, communicating, and collaborating with various colleagues (e.g., principal investigator, clinicians, medical staff, sponsors, contract research organizations (CROs), and neurology research staff, finance and billing professionals, and regulatory team) at various stages of each study assigned. The assistant professor - research is responsible for providing excellent customer service to both internal and external stakeholders by presenting a positive image of the department and University.
Independently and in collaboration, responsible for writing grants and serving as a co-Investigator/Principal Investigator on NIH-funded grants.
This description is a summary only and is describing the general level of work being performed, it is not intended to be all-inclusive. The duties of this position may change from time to time and/or based on business need. We reserve the right to add or delete duties and responsibilities at the discretion of the supervisor and/or hiring authority.
Knowledge, Skills and Abilities
NIH grant assembly
Histology (dissection of intact nervous tissue and cryosectioning); troubleshooting IHC with untested antibodies; western blot; cell culture of infected cell lines; Enterovirus D68 handling, expansion and titering; nucleic acid extraction, RT-PCR and qPCR; confocal microscopy; electron microscopy; mouse handling and injection (IM, IP, and IC).
Outstanding interpersonal and communication skills with the ability to work independently and within diverse team structures.
Respect patient privacy/rights and put patient safety first, excellent patient rapport for any clinically-related projects or human sample acquisition
A positive, motivated, engaged, and caring attitude
Great attention to detail and quality
Ability to work with colleagues and patients in a confidential and professional manner
Follow best practices in research (ICH guidelines, GCP, FDA guidelines)
Ability to follow and execute a study protocol and proactively prevent deviations
Ability to follow direction of the PI and direct supervisor, follow all department SOPs and department policies
Good documentation practices
Dedication to professional development and life-long learning
Ability to be adaptable, flexible, and to think on your feet
Adept at creative problem-solving
Proficient in Microsoft Office Suite (e.g., Word, Excel, PowerPoint), JMP pro or equivalent statistical analysis program, and Image J.
Salary and Benefits:
The salary range ( or hiring range ) for this position has been established at $85,000 - $100,000.
The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.
The above salary range ( or hiring range ) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.
Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.
Benefits: https://www.cu.edu/employee-services/benefits (https://apptrkr.com/get_redirect.php?id=4570222&targetURL=https://www.cu.edu/employee-services/benefits)
Total Compensation Calculator: http://www.cu.edu/node/153125 (https://apptrkr.com/get_redirect.php?id=4570222&targetURL=http://www.cu.edu/node/153125)
Diversity and Equity:
The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@ucdenver.edu (https://apptrkr.com/get_redirect.php?id=4570222&targetURL=hr.adacoordinator@ucdenver.edu) .
The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ+ community, and all veterans. The University of Colorado is committed to diversity and equality in education and employment.
The University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.
Vaccination Statement:
CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases (https://apptrkr.com/get_redirect.php?id=4570222&targetURL=https://www.cdc.gov/vaccines/schedules/downloads/adult/adult-combined-schedule.pdf) . If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program (https://apptrkr.com/get_redirect.php?id=4570222&targetURL=https://research.cuanschutz.edu/ehs/home/divisions/occupational-health/oh-enrollment) .
Qualifications
Minimum Qualifications
Applicants must meet minimum qualifications at the time of hire.
Ph.D. in neuroscience, virology, toxicology, or related field
Postdoctoral Fellowship in the fields of neuroscience and enterovirus pathogenesis.
3 years' experience in (1) enterovirus research; (2) Antiviral trials in a mouse model of enterovirus induced acute flaccid myelitis; (3) Collection of spinal cord tissue for IHC, PCR, and TCID50 analysis.
Experience writing grants (either training or research) which were successfully funded
Experience with all aspects of mouse colony management and proficiency in intramuscular, intraperitoneal, and intracerebral injection of postnatal day two mouse pups.
Experience preparing water- and oil- soluble drugs for ED50 / LD50 analysis in vivo, and IC50 assay in vitro.
Statistical expertise using MANOVA, mixed models, and survival plots for data with non-normal distribution, uneven sample sizes, censoring, repeated measures, and log transformations.
Preferred Qualifications
Expertise in pharmacokinetics/pharmacodynamics
Expertise in cellular anatomy of spinal cord neurons and glial cells
Experience in immunohisto- and cyto-chemistry, confocal microscopy and imaging software, basic tissue culture and virology techniques (infection, titers, stock preps), primary human neuron cultures, brain and spinal cord dissection, Western blot, cryotome sectioning, and qPCR of virus infected samples.
Special Instructions to Applicants: Applications are accepted electronically ONLY at www.cu.edu/cu-careers. Refer to requisition number: 27210. Application Materials Required: Cover Letter, Resume/CV, List of References Application Materials Instructions: Required Application Materials: To apply, please visit: http://www.cu.edu/cu-careers (https://apptrkr.com/get_redirect.php?id=4570222&targetURL=http://www.cu.edu/cu-careers) and attach: 1. A letter of application which specifically addresses the job requirements and outlines qualifications 2. A current CV/resume 3. List of five professional references (we will notify you prior to contacting both on and off-list references) Please be advised that the University does check references as part of the employment process. Please do not submit any of your application material (via email) to the job posting contact.
Job Category : Faculty
Primary Location : Aurora Department: U0001 -- Anschutz Med Campus or Denver - 20244 - SOM-NEUR GENERAL OPERATIONS
Schedule : Full-time
Posting Date : Aug 30, 2022
Unposting Date : Ongoing Posting Contact Name: Angela Kirkpatrick Posting Contact Email: neurology-hr@cuanschutz.edu (https://apptrkr.com/get_redirect.php?id=4570222&targetURL=neurology-hr@cuanschutz.edu) Position Number: 00801083
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The University of Colorado does not discriminate on the basis of race, color, national origin, sex, age, pregnancy, disability, creed, religion, sexual orientation, gender identity, gender expression, veteran status, political affiliation, or political philosophy. All qualified individuals are encouraged to apply.